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Conditions of optimal PDPN Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
Podoplanin is a type-1 transmembrane protein that belongs to Podoplanin family. PDPN expressed in various specialized cell types throughout the body. It highly expressed in placenta, lung, skeletal muscle and brain, weakly expressed in brain, kidney and liver. In placenta, PDPN expressed on the apical plasma membrane of endothelium, in lung, expressed in alveolar epithelium. PDPN physiological function is related to its mucin-type character. PDPN may be involved in cell migration and/or actin cytoskeleton organization. When expressed in keratinocytes, induces changes in cell morphology with transfected cells showing an elongated shape, numerous membrane protrusions, and major reorganization of the actin cytoskeleton, increased motility and decreased cell adhesion. It requires for normal lung cell proliferation and alveolus formation at birth and Induces platelet aggregation. Nevertheless, it doesn? have any effect on amino acid transport and the aquaporin-type water channels.
BP001149-PRO-626: Recombinant Human Podoplanin (PDPN) Protein
Source: E. coli-derived.
Recombinant Human Podoplanin (PDPN) Protein fused to a 20 a.a N-terminal His-Tag is a single, non-glycosylated polypeptide chain (99-207 a.a) containing 130 amino acids and having a molecular mass of 13.4 kDa.
Purity: >95.0% as determined by SDS-PAGE.
Formulation: The protein solution contains 20 mM Tris-HCl pH 7.5 & 0.1 M NaCl.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other PDPN Proteins:
Recombinant Human PDPN Protein
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