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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Recombinant human PDL1-Flag fusion protein, recombinant human PD1-Fc fusion protein (IgG1), and recombinant human PD1-His fusion protein are also available.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Source: HEK 293 cell-derived.
Recombinant PDL1-Fc protein is human PDL1 (amino acids 19-239) fused with mouse IgG1 Fc protein at the C-terminus.
Purity: >95% by SDS-PAGE under reducing conditions.
Formulation: 0.2 μM filtered solution of 50 mM Tris, 150 mM NaCl, pH 7.5.
Endotoxin Level: Less than 1 EU/ug of protein as determined by LAL method.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
1 month from date of receipt, 2 to 8°C as supplied.
3 months from date of receipt, -20°C to -70°C as supplied.
Background
Programmed Death Ligand 1 (PDL1) is a member of the growing B7 family of immune proteins that provide signals for both stimulating and inhibiting T cell activation. It is a 40kDa type 1 transmembrane protein that has been speculated to play a major role in suppressing the immune system during particular events such as pregnancy, tissue allografts, autoimmune disease and other disease states such as hepatitis. PD-L1 binds to its receptor, PD-1, found on activated T cells, B cells, and myeloid cells, to modulate activation or inhibition.
Other Recombinant PDL1 Protein:
Recombinant Human PDL1-FLAG Fusion Protein
Recombinant PD1 Protein:
Recombinant Human PD1-Fc Fusion Protein (IgG1)
Recombinant Human PD1-His Fusion Protein
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