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Home > Antibodies > A-Z Primary Antibodies > Paxillin Antibody (I)

Paxillin Antibody (I)

Paired box protein Pax-1; PAX-1; PAXI; paxillin; paxillin alpha

Catalog No. Product Name Size List Price (US$) Quantity
PA000077-PA1804 Paxillin Polyclonal Antibody 100 ug 350.00
Description

Background
The paxillin gene can be alternatively spliced to include 1 of 2 alternative exons, generating beta and gamma isoforms. Paxillin is a 68-kDa focal adhesion protein that is phosphorylated on tyrosine residues in fibroblasts in response to transformation by v-src, treatment with platelet-derived.growth factor, or cross-linking of integrins. The 68-kD protein (paxillin) is a cytoskeletal component that localizes to the focal adhesions at the ends of actin stress fibers in chicken embryo fibroblasts. It is also present in the focal adhesions of Madin-Darby bovine kidney (MDBK) epithelial cells but is absent, like talin, from the cell-cell adherens junctions of these cells.

PA000077-PA1804: Paxillin Polyclonal Antibody

Rabbit Polyclonal Antibody.
Applications: WB 0.1-0.5 ug/ml; IHC-P 0.5-1 ug/ml; IHC-F 0.5-1 ug/ml; ICC1 ug/ml.
Reactivity: Human, Rat, Mouse.
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of human PXN, identical to the related rat and mouse sequences.
Purification: Immunogen affinity purified.
Form of Antibody: Lyophilized.
Isotype: Rabbit IgG.

Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.

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