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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal p53 antibody performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Background
The p53 tumor antigen is found in increased amounts in a wide variety of transformed cells. The protein is also detectable in many actively proliferating, nontransformed cells, but it is undetectable or present at low levels in resting cells. This protein induces cell cycle arrest or apoptosis in response to sublethal or severe DNA damage, respectively, by differential transcription of target genes and through transcription-independent apoptotic functions. The p53 protein contains 393 amino acids. Human p53 tumour antigen is Locatedto band 17p13. p53 mutations are common in pancreatic cancer and are absent in chronic pancreatitis
PA000071-MA1078: p53 Monoclonal Antibody
Mouse Monoclonal Antibody.
Specificity/Sensitivity: Human. No cross reactivity with other proteins.
Applications: Western blot: At 0.5-1 ug/ml with the appropriate system to detect p53 in cells and tissues. Immunohistochemistry(P): At 0.5-2ug/ml to detect p53 in formalin fixed and paraffin embedded tissues. Immunohistochemistry(F): At 0.5-2ug/ml to detect p53 in formalin or acetone fixed tissues.
Reactivity: Human.
Immunogen: Recombinant human wild-type p53 protein.
Purification: Purified by the goat anti-mouse IgG affinity chromatography.
Form of Antibody: Lyophilized from 1.2% sodium acetate, with 2 mg BSA and 0.01 mg NaN3 as preservative.
Clone: IMD-53.
Isotype: Mouse IgG2a.
Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
Other p53 Antibodies:
p53 Polyclonal Antibody
p53 Polyclonal Antibody
p53 (Acetyl-Lys317) Polyclonal Antibody
p53 (Ab-6) Polyclonal Antibody
p53 (Ab-392) Polyclonal Antibody
p53 (Ab-382) Polyclonal Antibody
p53 (Ab-18) Polyclonal Antibody
p53 Proteins:
Recombinant Human Cellular tumor antigen p53 Protein
Recombinant Human Cellular tumor antigen p53 Protein
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