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Home > Proteins & Peptides > A-Z Proteins  > OTC Enzyme

OTC Enzyme

Ornithine Carbamoyltransferase, Ornithine transcarbamylase, OTCase, OCTD, EC 2.1.3.3

Catalog No. Product Name Size List Price (US$) Quantity
BP002809-ENZ-221 Recombinant Human Phosphate Cytidylyltransferase 2 Enzyme 5 ug 160.00
BP002809-ENZ-221 Recombinant Human Phosphate Cytidylyltransferase 2 Enzyme 50 ug 1200.00
Description

Introduction
OTC is a member of the ATCase/OTCase family. OTC has a key part in the urea cycle, catalyzing the second step in this pathway: the transformation of L-orthinine and carbamoyl phosphate to L-citrulline. In humans, the urea cycle is a vital pathway to detoxification of ammonia. Alterations in the gene encoding OTC are linked to the X-linked disorder OTCD (ornithine carbamoyltransferase deficiency). OTCD disorder of the urea cycle is characterized by hyperammonemia.

BP002808-ENZ-596: Recombinant Human Ornithine Carbamoyltransferase (OTC) Enzyme

Source: E. coli-derived.
A single polypeptide chain containing 347 amino acids (33-354) and having a molecular mass of 38.9 kDa. OTC is fused to a 25 amino acid His-tag at N-terminus.
Purity: > 90% as determined by SDS-PAGE.
Formulation: The OTC solution (0.5 mg/ml) contains 20 mM MES buffer (pH 6.0), 100 mM Nacl, 2 mM DTT and 10% glycerol.

Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.

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