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Conditions of optimal NY-ESO-1 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
NY-ESO-1, a member of the CT (cancer/testis) family, is a tumor-specific shared antigen with distinctive immunogenicity. NY-ESO-1 is expressed in testis and ovary and in a wide variety of cancers. It is also detected in uterine myometrium. The expression is from 18 weeks until birth in human fetal testis. Furthermore, in the adult testis, NY-ESO-1 is strongly expressed in spermatogonia and in primary spermatocytes, but not in post-meiotic cells or in testicular somatic cells (at protein level).
The molecular basis of T cell-mediated antitumor immunity has been elucidated by the identification of a number of tumor antigens recognized by CD8+ T cells. Among these antigens, NY-ESO-1 is of particular interest because both the cytotoxic T lymphocyte and antibody have been shown to react with this antigen.
BP002926-PRO-531: Recombinant Human NY Esophageal Squamous Cell Carcinoma 1 (NY-ESO-1) Protein
Source: E. coli-derived.
Recombinant Human NY Esophageal Squamous Cell Carcinoma 1 (NY-ESO-1) Protein shows a 49 kDa SDS-PAGE (including GST tag). Recombinant Human NY Esophageal Squamous Cell Carcinoma 1 (NY-ESO-1) Protein is purified by proprietary chromatographic techniques.
Formulation: NY-ESO-1 at 100 ug/ml in 50 mM Tris-HCl, pH 7.5 and 10 mM L-glutathione (reduced).
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
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