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Conditions of optimal NTAL Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction:
Linker for activation of T-cells family member 2, also known as Linker for activation of B-cells, Membrane-associated adapter molecule, Non-T-cell activation linker, Williams-Beuren syndrome chromosomal region 15 protein, Williams-Beuren syndrome chromosomal region 5 protein, LAB, NTAL, WBS15, WBSCR15, WBSCR5 and LAT2, is a single-pass type III membrane protein. LAT2 is highly expressed in spleen, peripheral blood lymphocytes, and germinal centers of lymph nodes. LAT2 is involved in FCER1 (high affinity immunoglobulin epsilon receptor) -mediated signaling in mast cells. It may also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activate of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2.
BP001305-PRO-827: Recombinant Human Non-T-cell activation linker (NTAL) Protein
Source: E. coli-derived.
Recombinant Human Non-T-cell activation linker (NTAL) Protein is a single, non-glycosylated, polypeptide chain containing 238 amino acids (27-243 a.a.) and having a molecular mass of 26.2 kDa. Recombinant Human Non-T-cell activation linker (NTAL) Protein is fused to a 21 amino acid His tag at N-terminus and is purified by standard chromatography.
Purity: >80.0% as determined by SDS-PAGE.
Formulation: NTAL Human solution containing 20 mM Trsi HCL pH 8, & 10% glycerol.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
Other NTAL Proteins:
Recombinant Human NTAL
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