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Conditions of optimal NRAS Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
NRAS binds GDP/GTP and has intrinsic GTPase activity. NRAS is a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This transport is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. NRAS is activated to a GTP-bound form by a GTPase activating protein and inactivated to a GDP-bound form by a guanine nucleotide-exchange factor. Defects in this NRAS gene result in juvenile myelomonocytic leukemia.
BP002929-PRO-794: Recombinant Human Neuroblastoma RAS Viral Oncogene Homolog (NRAS) Protein
Source: E. coli-derived.
Recombinant Human Neuroblastoma RAS Viral Oncogene Homolog (NRAS) Protein is a single, non-glycosylated polypeptide chain containing 186 amino acids (1-186 a.a.) and having a molecular mass of 20.8 kDa. Recombinant Human Neuroblastoma RAS Viral Oncogene Homolog (NRAS) Protein is purified by conventional chromatography.
Purity: >95.0% as determined by SDS-PAGE.
Formulation: The NRAS protein solution contains 20 mM Tris-HCl pH 7.5, 100 mM NaCl, and 10% glycerol.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
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