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Conditions of optimal NR5A1 Antibody performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
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Introduction
NR5A1 (Nuclear Receptor Subfamily 5, Group A, Member 1), also known as SF1 or FTZ1, is a member of the nuclear receptor family of intracellular transcription factors and is encoded by the NR5A1 gene. By linkage analysis using interspecific backcross mice, Swift and Ashworth (1995) mapped the Nr5a1 gene to mouse chromosome 2. Shen et al. (1994) proposed that SF1 regulates MIS in vivo and participates directly in the process of mammalian sex determination. SF-1 is a critical regulator of reproduction, regulating the transcription of key genes involved in sexual development and reproduction. Its targets include genes at every level of the hypothalamic-pituitary-gonadal axis, as well as many genes involved in gonadal and adrenal steroidogenesis.
PA006721-PA2062: NR5A1 Polyclonal Antibody
Rabbit Polyclonal Antibody.
Applications: WB 0.1-0.5 ug/ml IHC-P 0.5-1 ug/ml.
Reactivity: Human, Rat, Mouse.
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of human NR5A1, identical to the related rat and mouse sequences.
Purification: Immunogen affinity purified.
Form of Antibody: Each vial contains 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
Isotype: Rabbit IgG.
Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
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