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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal NMRAL1 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
NMRAL1 is a redox sensor protein which goes through reformation and subcellular rearrangement in reaction to alterations in intracellular NADPH/NADP+ levels. When the NADPH concentration is low the protein is found mostly as a monomer, and binds argininosuccinate synthase (ASS1), which takes part in nitric oxide synthesis. Association with ASS1 defects NMRAL1 activity and diminishes the production of nitric oxide, which then inhibits apoptosis. When the NADPH concentration is normal , the protein is found as a dimer and hides the binding site for ASS1.
BP002931-PRO-1131: Recombinant Human NmrA-like family domain containing protein 1 (NMRAL1) Protein
Source: E. coli-derived.
Recombinant Human NmrA-like family domain containing protein 1 (NMRAL1) Protein is a single polypeptide chain containing 323 amino acids (1-299) and having a molecular mass of 35.9 kDa. Recombinant Human NmrA-like family domain containing protein 1 (NMRAL1) Protein is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Purity: >95.0% as determined by SDS-PAGE.
Formulation: The NMRAL1 solution (0.5 mg/ml) contains 20 mM Tris-HCl buffer (pH 8.0), 0.15 M NaCl and 40% glycerol.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
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