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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal NF68 antibody performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Background
Neurofilaments are composed of 3 neuron-specific proteins with apparent molecular masses of 68 Kd (NFL), 125 kD (NFM) and 200 kD (NFH) on SDS-gel electrophoresis. And they have a role in the maturation of regenerating myelinated axons. Neurofilament 68 (NF68), also called Neurofilament rotein, Light Chain (NFL). It is one of the most abundant cytoskeletal omponents of the neuron.Mutations in this gene were reported as a cause for autosomal dominant Charcot-Marie-Tooth type 2E (CMT2E) linked to chromosome 8p21. NFL was identified repeatedly in both screenings and found to interact with Myotubularin-related 2 gene, MTMR2 in both Schwann cells and neurons.
PA000067-MA1070: NF68 Monoclonal Antibody
Mouse Monoclonal Antibody.
Specificity/Sensitivity: Human, pig, rat. No cross reactivity with other proteins.
Applications: Western blot: At 1-2ug /ml with the appropriate system to detect NF68 in cells and tissues. Immunohistochemistry(P): At 2-4ug /ml to detect NF68 in formalin fixed and paraffin embedded tissues. Immunohistochemistry(F): At 2-4ug /ml to detect NF68 in formalin or acetone fixed tissues.
Reactivity: Human, Rat, Pig.
Immunogen: Pig spinal cord.
Purification: Purified by the goat anti-mouse IgG affinity chromatography.
Form of Antibody: Lyophilized from 1.2% sodium acetate, with 2 mg BSA and 0.01 mg NaN3 as preservative.
Clone: NF-68.
Isotype: Mouse IgG1.
Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
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