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NF200 Antibody

Neurofilament 200 Antibody

Catalog No. Product Name Size List Price (US$) Quantity
PA000068-MA1071 NF200 (Phos. and Nonphos.) Monoclonal Antibody 100 ug 350.00
Description

Background

Neurofilaments are composed of 3 neuron-specific proteins with apparent molecular masses of 68 Kd (NFL), 125 kD (NFM), and 200 kD (NFH) on SDS-gel electrophoresis. Genomic clones for the largest human neurofilament protein (NF-H) were isolated, the intron/exon boundaries mapped and the entire protein-coding regions (exons) sequenced. mutations in neurofilaments have been linked to some forms of Charcot-Marie-Tooth disease (CMT)

PA000068-MA1071: NF200 (Phos. and Nonphos.) Monoclonal Antibody

Mouse Monoclonal Antibody.
Specificity/Sensitivity: Human, mouse, rat. No cross reactivity with other proteins.
Applications: Western blot: At 0.5ml with the appropriate system to detect NF200 in cells and tissues. Immunohistochemistry(P): At 1-2?g/ml to detect NF200 in formalin fixed and paraffin embedded tissues. Immunohistochemistry(F): At 1-2?g/ml to detect NF200 in formalin or acetone fixed tissues.
Reactivity: Human, Mouse, Rat.
Immunogen: C-terminal segment of enzymatically dephosphorylated pig Neurofilament 200.
Purification: Purified by the goat anti-mouse IgG affinity chromatography.
Form of Antibody: Lyophilized from 1.2% sodium acetate, with 2 mg BSA and 0.01 mg NaN3 as preservative.
Clone: NF-200.
Isotype: Mouse IgG1.

Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.

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