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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal NF-κB p65 antibody performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Background
The p65 (RELA) heterodimer is the most abundant form of NF-κB. This gene is located on 11q13, which consists of 10 exons and spans about 8.1 kb of DNA1. In rat sciatic nerves, the expression of the activated p65 subunit of NF-κB was high in the nuclei of premyelinating Schwann cells and then progressively declined until it was nearly absent in adults2. The transcriptional activity of NF-kappa-B is stimulated upon phosphorylation of its p65 subunit on serine-276 by protein kinase A (PKA). The transcriptional coactivator CBP /p300 associates with NF-kappa-B p65 through 2 sites, an N-terminal domain that interacts with the C-terminal region of unphosphorylated p65, and a second domain that
only interacts with p65 phosphorylated on serine-2763.
PA002563-PA1125: NF-κB p65 Polyclonal Antibody
Rabbit Polyclonal Antibody.
Specificity/Sensitivity: Human No cross reactivity with other proteins.
Applications: Western blot: At 1ug/ml with the appropriate system to detect NF-κBP65 in cells and tissues.
Immunogen: A synthetic peptide mapping at the N-terminal of human NF-κBP65, identical to the related rat and mouse sequence.
Purification: Immunogen affinity purified.
Form of Antibody: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
Reactivity: Human, Mouse, Rat.
Isotype: Rabbit IgG.
Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
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