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Conditions of optimal NDE1 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
NDE1 is a cytoplasmic protein which is a member of the nudE protein family. Phosphorylated during mitosis, NDE1 is critical for the formation and function of the mitotic spindle in M phase and functions to regulate the Dynein-mediated transport of kinetochore proteins, as well as centrosome duplication during interphase. NDE1 is believed to interact with NDEL1, LIS1 and Dynein IC1/2, cytosolic in a signaling pathway which regulates the formation of neurons and is fundamental to the development of the cerebral cortex.
BP002936-PRO-204: Recombinant Human Nuclear distribution protein nudE homolog 1 (NDE1) Protein
Source: E. coli-?derived.
Recombinant Human Nuclear distribution protein nudE homolog 1 (NDE1) Protein is a single, non-glycosylated polypeptide chain containing 355 amino acids (1-335 a.a.) and having a molecular mass of 39.9 kDa (Molecular weight on SDS-PAGE will appear higher). Recombinant Human Nuclear distribution protein nudE homolog 1 (NDE1) Protein is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Purity: >85% as determined by SDS-PAGE.
Formulation: The NDE1 solution (1 mg/ml) contains 20 mM Tris-HCl buffer (pH 8.0), 20% glycerol, 5 mM DTT and 0.2 M NaCl.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
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