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Conditions of optimal NCS1 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
NCS1 is part of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed primarily in neurons. NCS1 regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. NCS1 is related with secretory granules and modulates synaptic transmission and synaptic plasticity. NCS1 regulates GRK1 and substitutes for calmodulin. NCS1 stimulates PI4KB kinase activity and participates in long-term synaptic plasticity through its interaction with PICK1. NCS1 takes part in neuron differentiation through inhibition of the activity of N-type voltage-gated calcium channel.
BP002937-PRO-802: Recombinant Human Neuronal calcium sensor 1 (NCS1) Protein
Source: E. coli-?derived.
Recombinant Human Neuronal calcium sensor 1 (NCS1) Protein is a single, non-glycosylated, polypeptide chain containing 198 amino acids (1-190 a.a.) and having a molecular mass of 22.9 kDa. Recombinant Human Neuronal calcium sensor 1 (NCS1) Protein is fused to an 8 amino acid His Tag at C-Terminus and purified by proprietary chromatographic techniques.
Purity: >95% as determined by SDS-PAGE.
Formulation: The NCS1 solution contains 20 mM Tris-HCl pH 8, 1 mM DTT, and 10% glycerol.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
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