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N-Cadherin Antibody

NCAD Antibody

Catalog No. Product Name Size List Price (US$) Quantity
PA000064-MA1067 N-Cadherin Monoclonal Antibody 100 ug 350.00
Description

Background

N-cadherin (NCAD) is a member of the cadherin cell-cell adhesion receptor family that includes P-, E-,and R-cadherin and liver cell adhesion molecule (L-CAM). N-Cadherin,, also known as Cadherin-2,encodes a 907-amino acid protein that includes a 159-amino acid signal sequence. Human and mouse nucleotide sequences are 96% identical. Mouse Ncad gene consists of 16 exons dispersed over more than 200 kb of genomic DNA. Human N-cadherin gene contains 16 exons and its sequence is highly similar to both the mouse NCAD gene (including the large first and second introns) and other cadherin genes. N-cadherin is mapped to 18q11.2. Cadherin regulates dendritic spine morphogenesis.

PA000064-MA1067: N-Cadherin Monoclonal Antibody

Mouse Monoclonal Antibody.
Specificity/Sensitivity: Human, mouse, rat, rabbit, chicken. No cross reactivity with other proteins.
Applications: Western blot: At 2 ug/ml with the appropriate system to detect N-cadherin in cells and tissues. Immunohistochemistry(F): At 4 ug  /ml to detect N-cadherin in formalin or acetone fixed tissues.
Reactivity: Human, Mouse, Rat, Rabbit, Chicken.
Immunogen: Affinity purified chicken heart A-CAM.
Purification: Purified by the goat anti-mouse IgG affinity chromatography.
Form of Antibody: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
Clone: NC-17.
Isotype: Mouse IgGI.

Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.

Other N-Cadherin Antibody:
N-Cadherin Polyclonal Antibody

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