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Myosin Antibody

Catalog No. Product Name Size List Price (US$) Quantity
PA000062-MA1065 Myosin(Smooth) Monoclonal Antibody 100 ug 350.00
Description

Background

Myosin is composed of 2 heavy chains of about 200,000 daltons each and 4 light chains of about 20,000 daltons each. The light chains are of 2 distinct types: the phosphorylatable, regulatory, or MLC2 type, and the nonphosphorylatable, alkali, or MLC1 and MLC3 types (MYL1 according to the HGM symbols). Skeletal Myosin (Fast), also known as MYL1, mapped to the region 2q32.1-qter. Southern blots of a panel of hybrids containing different portions of human chromosome 16 localized the gene to 16p13.13-p13.12. Skeletal Myosin (slow), also known as light chain 3(MYL3), mapped to 3p. Fodor et al. (1989) found that the MYL3 gene has 7 exons, the last of which is completely untranslated 3-prime sequence.

PA000062-MA1065: Myosin (Smooth) Monoclonal Antibody

Mouse Monoclonal Antibody.
Specificity/Sensitivity: Human, rabbit, chicken. No cross reactivity with other proteins.
Applications: Western blot: At 0.25-0.5?g/ml with the appropriate system to detect myosin(smooth) in cells and tissues. Immunohistochemistry(P): At 0.5-1 ug/ml to detect myosin(smooth) in formalin fixed and paraffin embedded tissues. Immunohistochemistry(F): At 0.5-1 ug/ml to detect myosin(smooth) in formalin or acetone fixed tissues.
Reactivity: Human, rabbit, chicken.
Immunogen: Human uterus smooth muscle extract.
Purification: Purified by the goat anti-mouse IgG affinity chromatography.
Form of Antibody: Lyophilized from 1.2% sodium acetate, with 2 mg BSA and 0.01 mg NaN3 as preservative.
Clone: MS-13.
Isotype: Mouse IgG1.

Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.

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