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Conditions of optimal MYC Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
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Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
c-Myc is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of c-Myc have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
BP003017-PRO-087: Recombinant Human V-Myc Myelocytomatosis Viral Oncogene (MYC) protein
Source: E. coli-derived.
Recombinant Human V-Myc Myelocytomatosis Viral Oncogene (MYC) protein is fused to a C-terminal poly-arginine tag and purified by proprietary chromatographic techniques.
Predicted molecular mass: 48.8 kDa.
Purity: > 95.0% by SEC-HPLC and SDS-PAGE.
Formulation: lyophilized after extensive dialysis against PBS.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
Myc Antibodies:
Myc Polyclonal Antibody
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