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Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal MVD Enzyme performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
Diphosphomevalonate decarboxylase (MVD) catalyzes the conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate in one of the early steps in cholesterol biosynthesis. MVD decarboxylates and dehydrates its substrate while hydrolyzing ATP. MVD is expressed in the heart, skeletal muscle, lung, liver, brain, pancreas, kidney and placenta.
BP002509-ENZ-226: Recombinant Human Mevalonate Decarboxylase (MVD) Enzyme
Source: E. coli-derived.
A single, non-glycosylated polypeptide chain containing 420 amino acids (1-400) and having a molecular mass of 45.6 kDa. MVD is fused to a 20 amino acid His-tag at N-terminus.
Purity: > 85% as determined by SDS-PAGE.
Formulation: The MVD solution (0.5 mg/ml) contains 20 mM Tris-HCl buffer (pH8.0), 20% glycerol and 1 mM DTT.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
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