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Conditions of optimal MOG Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
Myelin oligodendrocyte glycoprotein (MOG) is a transmembrane protein, which is expressed exclusively in the CNS. MOG contains a single Ig-domain exposed to the extracellular space which allows autoantibodies easy access. MOG protein has been identified as a crucial autoantigen for multiple sclerosis in humans. MOG is capable to produce a demyelinating multiple sclerosis-like disease in experimental animals,namely experimental autoimmune encephalomyelitis (EAE) in rodents and monkeys.
BP001328-PRO-466: Recombinant Human Myelin oligodendrocyte glycoprotein (MOG) Protein
Source: E. coli-derived.
Myelin Oligodendrocyte Glycoprotein is a single, non-glycosylated polypeptide chain containing a total of 132 amino acids (Met + 30-154 a.a. + 6x His tag at C-terminus) and having a total molecular mass of 15.2 kDa.
Purity: > 95.0% by RP-HPLC and SDS-PAGE.
Formulation: The Myelin Oligodendrocyte Glycoprotein 0.5 mg/ml solution was lyophilized from 20 mM sodium acetate buffer pH-4 and 0.3 M sodium chloride.
Reconstitution: It is recommended to reconstitute the lyophilized MOG in sterile 10 mM Acetic acid not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other MOG Proteins:
Recombinant Human MOG Protein
Recombinant Human MOG Protein
MOG Peptide (35-55)
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