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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal MIP 1β Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
Macrophage Inflammatory Proteins belong to the family of chemotactic cytokines known as chemokines. In humans, there are two major forms, MIP-1a and MIP-1b that are now also named CCL3 and CCL4. Both factors are produced by macrophages after they are stimulated with bacterial endotoxins. MIP-1a and MIP-1b activate human granulocytes (neutrophils, eosinophils and basophils) which can lead to acute neutrophilic inflammation. MIP-1a and MIP-1b induce synthesis and release of other pro-inflammatory cytokines such as interleukin-1 (IL-1), IL-6 and TNF-alpha from fibroblasts and macrophages. CCL3 and CCL4 genes are both located on human chromosome 17.
BP000282-CHM-276: Recombinant Human MIP-1β (CCL4) Protein
Source: E. coli-derived.
N-terminal sequence analysis: Ala-Pro-Met-Gly-Ser.
Predicted molecular mass: 7620 Da.
The Activity is calculated by the ability to chemoattract Human blood monocytes using a concentration of 5-20 ug/ml corresponding to a Specific Activity of 50,000-200,000 IU/mg.
Purity > 99%, by SDS--PAGE and RP-HPLC.
Formulation: Lyophilized from a concentrated (1 ug/ml) solution in water containing no additives.
Reconstitution: It is recommended to reconstitute the lyophilized Macrophage Inflammatory Protein-1b in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other MIP 1 beta Protein:
Recombinant mouse MIP-1β (CCL4) protein
Recombinant mouse MIP-1β (CCL4) Fc fusion protein
Recombinant rat MIP-1β (CCL4) protein
MIP 1 beta Antibody:
MIP-1β (CCL4) polyclonal antibody
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