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Conditions of optimal MEMO1 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
Mediator of ErbB2-driven cell motility 1 (MEMO1) is a member of the UPF0103 family. MEMO1 regulates cell migration by transmitting extracellular chemotactic signals to the microtubule cytoskeleton. Furthermore, MEMO1 controls the localization of APC and CLASP2 to the cell membrane, using the regulation of GSK3B activity. MEMO1 is essential for breast carcinoma cell migration, suggesting a key role in tumorigenesis. MEMO1 is also a mediator of ERBB2 signaling.
BP002697-PRO-1148: Recombinant Human Mediator of Cell Motility 1 (MEMO1) protein
Source: Escherichia Coli-derived.
Recombinant Human Mediator of Cell Motility 1 (MEMO1) protein is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Predicted molecular mass: 36.4 kDa.
Purity: > 95.0% by SDS-PAGE.
Formulation: MEMO1 protein solution (0.5 mg/ml) containing 20 mM Tris-HCl buffer, pH8.0, 50% glycerol, 5 mM DTT, 300 mM NaCl and 2 mM EDTA.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
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