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Conditions of optimal MAD2L1 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
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Fax: 1-617-606-5019
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Introduction
MAD2L1-binding protein (MAD2L1) is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is vital for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment and inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate.
BP001769-PRO-934 : Recombinant Human MAD2 Mitotic Arrest Deficient-Like 1 (MAD2L1) Protein
Source: Escherichia Coli-derived.
Recombinant Human MAD2 Mitotic Arrest Deficient-Like 1 (MAD2L1) Protein is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Predicted molecular mass: 25.7 kDa.
Purity: >95% by SDS-PAGE.
Formulation: MAD2L1 protein solution (0.5 mg/ml) containing 20 mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1 M NaCl and 1 mM DTT.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
MAD2L1 Antibodies:
MAD2L1 Polyclonal Antibody
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