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Conditions of optimal LYVE1 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
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Or leave a message with a formal purchase
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Introduction
LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE-1 molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE-1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.
BP000655-PKA-349: Recombinant Human Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1 (LYVE1) Protein (25-235 a.a)
Source: High Five insect cells-derived.
A single, glycosylated polypeptide chain containing 229 amino acids and having a molecular mass of 24.8 kDa.
Purity: > 90% by RP-HPLC and SDS-PAGE.
Formulation: The LYVE1 protein solution contains 20 mM Tris buffer pH-7.5 and 10% Glycerol.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other LYVE1 Proteins:
Recombinant Mouse LYVE1 Protein, Sf9
Recombinant Human LYVE1 Protein
Recombinant Human LYVE1 Protein
Recombinant Human LYVE1 Protein, Sf9
LYVE1 Antibodies
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