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Conditions of optimal LBP Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
Lipopolysaccharide binding protein (LBP) is a plasma protein, belongs to a member of structurally and functionally related proteins which includes bactericidal permeability-increasing protein (BPI), plasma cholesteryl ester transfer protein (CETP) and phospholipid transfer protein (PLTP). It is involved in the acute-phase immunologic response to gram-negative bacterial infections. In cooperation with BPI. LBP binds LPS and interacts with the CD14 receptor, most likely playing a role in regulating LPS-dependent monocyte responses. Studies suggest that LBP is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. Finally, t The LBP gene is found on chromosome 20, directly downstream of the BPI gene.
BP001729-PRO-538: Recombinant Human Lipopolysaccharide-Binding Protein (LBP)
Source: CHO-derived.
Recombinant Human Lipopolysaccharide-Binding Protein (LBP) is produced from human LBP transfected CHO-cells in serum free medium.
Activity: Up to 0.2 ug/ml LBP mediates binding of FITC-LPS (0.5 mg/ml) to CD14+CHO transfectants (FACS).
Formulation: Recombinant Human LBP was lyophilized from a protein solution (0.25 mg/ml) containing phosphate-buffered saline, pH 7.2.
Reconstitution: Every 10 ug of recombinant human LBP should be reconstituted using 40 ul of sterile H2O. The solution can be than diluted with phosphate-buffered saline or other buffers.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other LBP Proteins:
Recombinant Mouse LBP Protein
Recombinant Human LBP Protein
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