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Conditions of optimal KLRC2 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
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Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
KLRC2 has a part as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. The group, designated KLRC (NKG2) are expressed mainly in natural killer (NK) cells and encodes a family of transmembrane proteins categorized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The KLRC (NKG2) gene family is situated inside the NK complex, a region which holds a few C-type lectin genes specially expressed on NK cells. KLRC2 alternative splice variants are known but their full-length nature is yet to be determined.
BP002472-PRO-1190: Recombinant Human Killer Cell Lectin-Like Receptor Subfamily C, Member 2 (KLRC2) Protein
Source: E. coli-derived.
A single polypeptide chain containing 183 amino acids (94-231) and having a molecular mass of 18.4 kDa. KLRC2 is fused to a 24 amino acid His-tag at N-terminus.
Purity: > 85% as determined by SDS-PAGE.
Formulation: The KLRC2 solution (0.5 mg/ml) contains 20 mM Tris-HCl buffer (pH 8.0), 4 M urea and 10% glycerol.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
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