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Conditions of optimal KLRB1 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
KLRB1 has an inhibitory role on natural killer (NK) cells cytotoxicity which are lymphocytes who facilitate cytotoxicity and secrete cytokines subsequent to immune stimulation. Some genes of the C-type lectin superfamily, like the rodent NKRP1 family of glycoproteins, are expressed by NK cells and take part in NK cell function regulation. KLRB1 holds an extracellular domain with a few characteristic motifs of C-type lectins, a transmembrane domain, and a cytoplasmic domain. Due to its external C terminus KLRB1 is considered to be a type II membrane protein.
BP002471-PRO-1189: Recombinant Human Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) Protein
Source: E. coli-derived.
A single polypeptide chain containing 183 amino acids (67-225) and having a molecular mass of 21.0 kDa. KLRB1 is fused to a 24 amino acid His-tag at N-terminus.
Purity: > 85% as determined by SDS-PAGE.
Formulation: The KLRB1 solution (1 mg/ml) contains 20 mM Tris-HCl buffer (pH 8.0), 4 M urea and 10% glycerol.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
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