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Conditions of optimal KLK11 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
Human Kallikrein 11 (KLK11) is a member of tissue kallikrein family which are extracellular serine proteases consisting of 15 members. Two isoforms of KLK11 are differentially expressed. Isoform 1 is predominantly expressed in brain and isoform 2 is preferentially expressed in prostate. Isoform 1 consists of a signal peptide,a short pro peptide and the mature chain.Isoform 2 contains an extra 32 amino acid N terminal to full-length isoform 1.KLK11 is a novel marker for ovarian and prostate cancer carcinomas. KLK11 can be activated by thermolysin and is active against a thioester substrate.
BP000647-ENZ-511: Recombinant Human Kallikrein-11 (KLK11) Protein
Source: HEK 293-F Cells-derived.
A single, glycosylated, polypeptide chain having a molecular weight of 25.6kDa though on SDS-PAGE migrates at about 41kDa due to the glycosilation.
KLK11 specific activity is greater than 2200 pmoles/min/?g when measure with 100 uM colormetric peptide substrate (D-Val-Leu-Lys-ThioBenzyl ester) and 1 ?g of activated enzyme.
Purity: > 95% by SDS-PAGE.
Formulation: The KLK11 protein was lyophilized from a 0.2 um filtered solution containing no additives or preservatives.
Reconstitution: It is recommended to reconstitute the lyophilized KLK11 in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other KLK11 Proteins:
Recombinant Human KLK11 Protein
KLK11 Antibodies:
KLK11 Polyclonal Antibody
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