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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal ITGA1 antibody performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Background
Integrin alpha 1 (ITGA1) chain associates with the beta 1 (ITGB1) chain to form a heterodimer that unctions as a dual laminin/collagen receptor in neural cells and hematopoietic cells. ITGA1 has a 06-amino acid I domain in its N-terminal half, followed by 3 divalent cation-binding sites and a -terminal transmembrane domain with a short cytoplasmic tail. It also has 28 potential N-glycosylation ites. Human ITGA1 was expressed in a mouse fibroblast cell line as a 180-kD protein. ITGA1 is involved in the early remodeling of osteoarthritic cartilage and plays an essential role in the regulation of esenchymal stem cell proliferation and cartilage production. It also plays an essential role in the egulation of MSC proliferation and cartilage production.
PA000115-PA1045: ITGA1 Polyclonal Antibody
Rabbit Polyclonal Antibody.
Specificity/Sensitivity: Human, mouse, rat. No cross reactivity with other roteins.
Applications: Western blot: At 0.1-0.5 ug/ml with the appropriate system to detect ITGA1 in cells and tissues.
Reactivity: Human, Mouse, Rat.
Immunogen: A synthetic peptide corresponding to a sequence at the N-terminal of human ITGA1, identical to the related rat and mouse sequences.
Purification: Immunogen affinity purified.
Form of Antibody: Each vial contains 50% glycerol, 0.9 mg NaCl, 0.2 mg Na2HPO4.
Isotype: Rabbit IgG.
Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
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