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Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal IPP Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
Intracisternal A particle-promoted polypeptide (IPP) is a 66kDa protein (584 amino acids), which contains an N-terminal POZ protein-protein interaction domain and a C-terminal kelch repeat domain consisting of six tandem arranged repeats. The POZ domain (also called BTB domain) is present near the N-terminus of a fraction of zinc finger proteins and in protein that contain the pfam01344 motif such as kelch and pox virus proteins. The BTB/POZ domain mediates homomeric dimerization and in some instances heteromeric dimerization. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-coR and SMRT.
BP002675-PRO-436: Recombinant Human Intracisternal A Particle-Promoted Polypeptide (IPP) protein
Source: Escherichia Coli-derived.
IPP-POZ Human Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 157 amino acids & having a molecular mass of 17.3 kDa.
Purity: > 95.0% by RP-HPLC and SDS-PAGE.
Formulation: The protein (1 mg/ml) containing 10 mM HEPES (pH 7.4) and 25 mM NaCl.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
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