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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal IL36B Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
Human IL-36b belongs to the IL-1 family that includes IL-1b, IL-1a, IL-1ra, IL-18, IL-36ra (IL1F5), IL-36b (IL1F8), IL-36g (IL1F9), IL-37 (IL1F7) and IL-38 (IL-1F10). The IL-1 family members display a 12 b-strand, b-trefoil configuration, and are thought to have ascended from a mutual ancestral gene. IL-36 beta is known to be actively secreted. Cells expressing IL-36 beta include resting and activated monocytes and B cells. The receptor for IL-36 beta is a blend of IL-1 Rrp2 and IL-1 RAcP. Recombinant IL-36 beta stimulates processes involving NF-kB and MAPK in an IL-1 Rrp2-dependent manner.
BP002451-CYT-159: Recombinant Human Interleukin-36 Beta (IL36B) Protein
Source: E. coli-derived.
A single, non-glycosylated, polypeptide chain containing 157 amino acids and having a molecular mass of 17.7 kDa.
Measured by its binding ability in a functional ELISA to bind recombinant human IL-1 Rrp2 Fc Chimera.
Purity: > 95.0% as determined by SDS-PAGE.
Formulation: Lyophilized from a 0.2 um filtered concentrated solution in 1x PBS, pH 7.4.
Reconstitution: It is recommended to reconstitute the lyophilized IL36B in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other IL36B Proteins:
Recombinant Mouse Interleukin-36 Beta Protein
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