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IL-8 Protein

Interleukin-8, CXCL8, Monocyte-derived neutrophil chemotactic factor, T-cell chemotactic factor, GCP-1, MDNCF, NAP-1

Catalog No. Product Name Size List Price (US$) Quantity
BP000271-CHM-340 Recombinant Porcine IL-8 (1-72 a.a) Protein 10 ug 160.00
BP000271-CHM-340 Recombinant Porcine IL-8 (1-72 a.a) Protein 100 ug 1100.00
Description

Introduction
Interleukin-8 (IL-8) is a chemokine produced by macrophages and other cell types such as epithelial cells. It is also synthesized by endothelial cells, which store IL-8 in their storage vesicles, the Weibel-Palade bodies. When first encountering an antigen, the primary cells to encounter it are the macrophages who phagocytose the particle. Upon processing, they release chemokines to signal other immune cells to come in to the site of inflammation. IL-8 is one such chemokine. It serves as a chemical signal that attracts neutrophils at the site of inflammation, and therefore is also known as Neutrophil Chemotactic Factor.

BP000271-CHM-340: Recombinant Porcine Interleukin-8 (IL-8) Protein

Source: E. coli-derived.
Predicted molecular mass: 8291 Dalton.
The biological activity of IL8 was determined by the dose dependent mobilization of intracellular calcium (calcium flux) with human neutrophils and was found to be >1.0 ug/ml corresponding to a Specific Activity of 1,000,000 IU/mg.
Purity: > 95% by SDS-PAGE and RP-HPLC.
Formulation: Lyophilized from a concentrated (1 ug/ml) solution in water containing no additives.
Reconstitution: It is recommended to reconstitute the lyophilized Interleukin 8 in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.

Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.

Other IL-8 Proteins:
Recombinant Human IL-8 (1-77 a.a) Protein, His Tag
Recombinant Human IL-8 (8-79) Protein
Recombinant Human IL-8 (2-79) Protein
Recombinant Human IL-8 (1-77 a.a.) Protein, Pichia
Recombinant Human IL-8 (1-77 a.a) Protein
Recombinant Human IL-8 (1-72 a.a.) Protein

IL-8 Antibodies:
IL-8 Polyclonal Antibody
IL-8 Monoclonal Antibody

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