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IL-17 Protein

Interleukin-17, CTLA-8, IL-17A, Cytotoxic T-lymphocyte-associated antigen 8

Catalog No. Product Name Size List Price (US$) Quantity
BP000140-CYT-378 Recombinant Mouse IL-17 Protein 25 ug 160.00
BP000140-CYT-378 Recombinant Mouse IL-17 Protein 1 mg 2800.00
Description

Introduction
IL17 is a proinflammatory cytokine produced by activated T cells. IL-17 regulates the activities of NF-kappaB and mitogen-activated protein kinases. Interleukin-17 can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

BP000140-CYT-378: Recombinant Mouse Interleukin-17 (IL-17) Protein

Source: E. coli-derived.
Predicted molecular mass: 30 kDa.
The ED50 as determined by the dose-dependant induction of IL-6 production in cultured mouse NIH 3T3 fibroblasts was found to be 0.4 ng/ml, corresponding to a specific activity of 2,500,000 units/mg.
Purity: > 98% by SDS-PAGE and RP-HPLC.
Formulation: Lyophilized from a concentrated (1 mg/ml) solution containing no additives.
Reconstitution: It is recommended to reconstitute the lyophilized Interleukin 17 in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.

Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.

Other IL-17 Proteins:
Recombinant Rat IL-17 Protein
Recombinant Human IL-17 Protein, His Tag

IL-17 ELISA Kits:
Mouse IL-17 ELISA Kit
Human IL-17 ELISA Kit

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