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Conditions of optimal EK Enzyme performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
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Source: recombinant human CD319 / CRACC / SLAMF7 protein (Ser23-Met226) was expressed in mammalian cells with a mFc tag at the C-terminus.
Accession: Q9NQ25
Predicted molecular mass: 48.8 kDa. Due to glycosylation, the recombinant human CD319 / CRACC / SLAMF7 protein migrates to 68-78 kDa based on the Bis-Tris PAGE result.
Endotoxin: Less than 1 EU per ug by the LAL method.
Formulation: The recombinant human CD319 / CRACC / SLAMF7 protein was lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as protectant before lyophilization.
Purity: > 95% by SDS-PAGE and HPLC.
Shipping: The recombinant human CD319 / CRACC / SLAMF7 protein is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage:
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Background
CD2-like receptor activating cytotoxic cells (CRACC), also known as CS1, novel Ly9, SLAMF7, and CD319, is a 65-75 kDa type I transmembrane glycoprotein in the SLAM subgroup of the CD2 family.Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response.
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