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HTLV1 Protein

Human T-lymphotropic virus

Catalog No. Product Name Size List Price (US$) Quantity
BP000447-HIV-108 Recombinant HTLV-1 p24 Core 100 ug 160.00
BP000447-HIV-108 Recombinant HTLV-1 p24 Core 500 ug 600.00
BP000447-HIV-108 Recombinant HTLV-1 p24 Core 1000 ug 1000.00
Description

Introduction
Human T-lymphotropic virus (HTLV) is a human, single-stranded RNA retrovirus that causes T-cell leukemia and T-cell lymphoma. The virus activates a subset of T-helper cells called Th1 cells. The result is a proliferation of Th1 cells and overproduction of Th1 related cytokines (mainly IFN-gamma and TNF-alpha). Feedback mechanisms of these cytokines cause a suppression of the Th2 lymphocytes and a reduction of Th2 cytokine production (mainly IL-4, IL-5, IL-10 and IL-13). The end result is a reduction in the ability of the infected host to mount an adequate immune response to invading organisms that require a predominantly Th2 dependant response (these include parasitic infections and production of mucosal and humoral antibodies).

BP000447-HIV-108: Recombinant Core HTLV-1 p24

Source: E. coli-derived.
Predicted molecular mass: 24 kDa.
Specificity: Immunoreactive with all sera of HTLV-1 infected individuals.
Purity > 95%, by 10% PAGE and RP-HPLC.
Formulation: 50 mM NaPO4 pH 6.0, containing 1 mM DTT & 1 mM EDTA.
Applications: WB, ELISA.

Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.

Other HTLV1 Proteins:
Recombinant HTLV-1 Mosaic
Recombinant HTLV-I gp46 Mosaic
Recombinant HTLV-1 gp21
Recombinant HTLV-1 + 2
Recombinant HTLV-1 Envelope
Recombinant HTLV-1 p24

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