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Conditions of optimal HSPA8 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
HSPA8 is part of the heat shock protein 70 family which includes both heat-inducible and constitutively expressed proteins (heat-shock cognate proteins). HSPA8 is a heat-shock cognate protein that binds to nascent polypeptides to facilitate correct folding. HSPA8 plays a role as an ATPase in the disassembly of clathrin-coated vesicles through transport of membrane components through the cell. HSPA8 is expressed in colon cancer cells, HSPA8 takes part in reovirus outer capsid disassembly, through membrane penetration, to plan the entering particle for gene expression and replication. serum HSPA8 concentrations are reduced in normal human pregnancy. HSPA8 plays a role in androgen action on dermal papilla cells. HSPA8 is directly linked with Influenza virus matrix protein 1 and thus required for viral production.
BP002303-HSP-026: Recombinant Human Heat Shock 70 kDa Protein-8 (HSPA8)
Source: E. coli-derived.
Recombinant Human HSPA8 proteein is a single, non-glycosylated polypeptide chain containing 666 amino acids (1-646 a.a.) and having a molecular mass of 73.1 kDa. Recombinant Human HSPA8 proteein is fused to 20 amino acid His Tag at N-terminus and purified by convential chromatogrpahy techniques.
Purity: > 90.0% as determined by SDS-PAGE.
Formulation: The HSC70 protein solution contains 20 mM Tris, pH-8 & 10% Glycerol.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
HSPA8 Antibodies:
HSC 70 (HSPA8) Polyclonal Antibody
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