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Conditions of optimal HSP90 Alpha Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
HSP90 has been identified in the cytosol, nucleus and endoplasmic reticulum, and is reported to exist in many tissue types. In several tissues, including smooth muscle, HSP90 comprises up to 2% of total cellular protein. HSP90 functions as a dimer, assembled as part of heterocomplex. It possesses ATP-binding site and low ATPase activity. HSP90 is able to associate with actin filaments in certain conditions. Another important property of HSP90 is the binding of unoccupied steroid hormone receptors. HSP90 has been characterized as a molecular chaperone able to keep the target protein in a folding-competent state. It has an enhanced chaperone activity in oligomeric form at high temperatures. HSP90 function is sensitive to bivalent cations concentration.
BP001997-HSP-090: Recombinant Human Heat Shock Protein-90 Alpha (HSP90 Alpha)
Source: E. coli-derived.
Recombinant Human HSP-90 protein is a single,non-glycosylated polypeptide chain containing 732 amino acids and having a molecular mass of 86.8 kDa. Recombinant Human HSP-90 protein is expressed with a 20 amino acid His tag at N-Terminus and purified by proprietary chromatographic techniques.
Purity: > 90.0% as determined by RP-HPLC abd SDS-PAGE.
Formulation: The HSP90 protein solution contains 20 mM Tris-HCl, pH-7.4 and 100 mM NaCl.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
HSP90A Antibodies:
HSP90 Alpha Monoclonal Antibody
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