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Conditions of optimal HSP105 antibody performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
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Fax: 1-617-606-5019
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Or leave a message with a formal purchase
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Background
HSP105 (HEAT-SHOCK 105/110-KD PROTEIN 1),also called HSPH1 or HSP110, is a protein that in humans is encoded by the HSPH1 gene. Immunohistochemical analysis localizes HSP105 mainly in the cytoplasm. Database analysis indicates that both HSP105 isoforms are highly conserved during evolution. By analysis of radiation hybrids and human/rodent hybrid cell lines, the HSPH1 gene is mapped to chromosome 13.Both HSP105-alpha and HSP105-beta are upregulated in HeLa cells exposed to heat shock. HSP105-alpha, but not HSP105-beta, is also upregulate in response to other cell stresses. Following heat shock, HSP105 relocalizes from a cytoplasmic to perinuclear position. Besides,HSP110 may thus constitute a major determinant for both prognosis and treatment response in colorectal cancer.
PA001992-PA1608: HSP105 Polyclonal Antibody
Rabbit Polyclonal Antibody.
Applications: WB: 0.1-0.5 ug/ml IHC-P: 0.5-1 ug/ml.
Reactivity: Human, Mouse, Mouse.
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of human HSP105, different
from the related mouse sequence by one amino acid and different from the related rat sequence by two amino acids.
Purification: Immunogen affinity purified.
Form of Antibody: Lyophilized.
Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
Other HSP105 Antibody:
HSP105 Polyclonal Antibody
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