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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal HMGN1 Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Introduction
HMGN1 binds to the inner side of the nucleosomal DNA therefore changing the interaction between the DNA and the histone octamer. HMGN1 participates in the development which maintains transcribable genes in an exceptional chromatin conformation. HMGN1 inhibits the phosphorylation of nucleosomal histones H3 and H2A by RPS6KA5/MSK1 and RPS6KA3/RSK2.
BP002316-PRO-821: Recombinant Human High-Mobility Group Nucleosome Binding Domain 1 (HMGN1) Protein
Source: E. coli-derived.
Recombinant Human HMGN1 protein is a single, non-glycosylated, polypeptide chain containing 108 amino acids (1-100 a.a.) and having a molecular mass of 11.7 kDa. HMGN1 protein is fused to a 8 amino acid His-Tag at C-terminus and purified by standard chromatography.
Purity: > 95% as determined by SDS-PAGE.
Formulation: Human HMGN1 solution containing 20 mM Trsi HCL pH-8, 1 mM DTT, 0.1 M NaCl, 0.1 mM PMSF & 20% glycerol.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
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