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HDDC3 Protein

HD domain containing 3, Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1, Metazoan SpoT homolog 1, MESH1

Catalog No. Product Name Size List Price (US$) Quantity
BP002547-ENZ-184 Recombinant Human HD domain containing 3 Protein 20 ug 160.00
BP002547-ENZ-184 Recombinant Human HD domain containing 3 Protein 1 mg 2700.00
Description

Introduction
Guanosine-3',5'-bis(diphosphate)-pyrophosphohydrolase MESH1 (HDDC3) contains an active site for ppGpp hydrolysis and a conserved His-Asp-box motif for Mn(2+) binding. In accordance with its structure, HDDC3 effectively catalyzes the hydrolysis of guanosine 3',5'-diphosphate (ppGpp) both in vitro and in vivo. In addition, HDDC3 suppresses SpoT-deficient lethality and RelA-induced delayed cell growth in bacteria.

BP002547-ENZ-184: Recombinant Human HD domain containing 3 (HDDC3) Protein

Source: E. coli-derived.
A single, non-glycosylated polypeptide chain containing 160 amino acids (1-140) and having a molecular mass of 17.9 kDa. HDDC3 is fused to a 20 amino acid His-tag at N-terminus.
Purity: > 90.0% as determined by SDS-PAGE.
Formulation: The HDDC3 solution (0.5 mg/ml) contains 20 mM Tris-HCl buffer (pH8.0), 40% glycerol, 0.15 M NaCl and 1 mM DTT.

Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.

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