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HDAC2 Antibody

Histone deacetylases 2 Antibody

Catalog No. Product Name Size List Price (US$) Quantity
PA000375-PA1350 HDAC2 Polyclonal Antibody 100 ug 350.00
Description

Background

Histone deacetylase 2 is an enzyme that in humans is encoded by the HDAC2 gene. This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes and are responsible for the deacetylation of lysine residues on the N-terminal region of the core histones (H2A, H2B, H3 and H4). This protein also forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Betz et al. (1998) performed PCR using HDAC2-specific primers to screen a somatic cell hybrid mapping panel. They mapped the HDAC2 gene to human chromosome 6q21, a region of the genome altered in some cancers, including retinoblastoma.

PA000375-PA1350: HDAC2 Polyclonal Antibody

Rabbit Polyclonal Antibody.
Specificity/Sensitivity: Human,rat,mouse. No cross reactivity with other proteins.
Applications: WB 1 ug/ml.
Reactivity: Human, Rat, Mouse.
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of human HDAC2 (464-478 aa), identical to the related mouse and rat sequence.
Purification: Immunogen affinity purified.
Form of Antibody: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
Isotype: Rabbit IgG.

Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.

Other HDAC2 Antibodies:
HDAC2 Polyclonal Antibody
HDAC2 Polyclonal Antibody
HDAC2 (Ab-394) Polyclonal Antibody

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