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HCV NS5B Protein

Hepatitis C Virus NS5B

Catalog No. Product Name Size List Price (US$) Quantity
BP002843-HCV-269 Recombinant Hepatitis C Virus NS5B Protein 100 ug 160.00
BP002843-HCV-269 Recombinant Hepatitis C Virus NS5B Protein 500 ug 600.00
BP002843-HCV-269 Recombinant Hepatitis C Virus NS5B Protein 1000 ug 1200.00
Description

Introduction
HCV is a small 50 nm, enveloped, single-stranded, positive sense RNAvirus in the family Flaviviridae.
HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes(1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6).

BP002843-HCV-269: Recombinant Hepatitis C Virus NS5B (HCV NS5B) Protein

Source: E. coli-derived.
Recombinant protein contains the full length of the NS5B immunodominant regions and fused to a 6xHis tag at C-Terminus.
Specificity: Immunoreactive with sera of HCV-infected individuals.
Purity > 95% pure as determined by SDS-PAGE.
Formulation: 1.5 M urea, 25 mM Tris-HCl pH 8.0, 0.2% Triton-X and 50% Glycerol.
Applications: ELISA, WB.

Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.

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