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Conditions of optimal HBXIP Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
Hepatitis B virus x interacting protein (HBXIP) forms a complex with the C-terminus of hepatitis B virus X (HBX) protein. HBXIP negatively regulates HBX activity and changes the replicative life cycle of the virus. Furthermore, HBXIP is involved in bipolar spindle formation and regulates centrosome dynamics and cytokinesis in cells, possibly due to interaction with Dynein light chain. HBXIP is highly expressed in the skeletal and cardiac muscle, followed by pancreas, kidney, liver, brain, placenta and lung. HBXIP has elevated levels in both cancerous and non-cancerous liver tissue of patients with chronic HBV infection compared with hepatic tissue without HBV infection.
BP002834-HBV-235: Recombinant Human Hepatitis B Virus x Interacting Protein (HBXIP)
Source: E. coli-derived.
A single polypeptide chain containing 197 amino acids (aa 1-173) and having a molecular mass of 20.7 kDa. HBXIP is fused to a 24 amino acid His-tag at N-terminus.
Purity > 90% as determined by SDS-PAGE.
Formulation: The HBXIP solution (1 mg/ml) contains 20 mM Tris-HCl buffer (pH 8.0), 0.1 M NaCl, 10% glycerol and 1 mM EDTA.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
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