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Home > Proteins & Peptides > A-Z Proteins  > HAV P3C Protein

HAV P3C Protein

Hepatitis A virus polyprotein

Catalog No. Product Name Size List Price (US$) Quantity
BP000411-HAV-231 Recombinant HAV P3C 100 ug 160.00
BP000411-HAV-231 Recombinant HAV P3C 500 ug 600.00
BP000411-HAV-231 Recombinant HAV P3C 1000 ug 1000.00
Description

Introduction
Forty-two antigenic domains were identified across the hepatitis A virus (HAV) polyprotein by using a set of 237 overlapping 20-mer synthetic peptides spanning the entire HAV polyprotein. Nineteen antigenic domains were found within the structural proteins, and 22 were found within the nonstructural proteins, with 1 domain spanning the junction of VP1 and P2A proteins. Five of these domains were considered immunodominant, as judged by both the breadth and the strength of their immunoreactivity. One domain is located within the VP2 protein at position 57-90 aa. A second domain, located at position 767-842 aa, contains the C-terminal part of the VP1 protein and the entire P2A protein. A third domain, located at position 1403-1456 aa, comprises the C-terminal part of the P2C protein and the N-terminal half of the P3A protein. The fourth domain, located at position 1500-1519 aa, includes almost the entire P3B, and the last domain, located at position 1719-1764 aa, contains the C-terminal region of the P3C protein and the N-terminal region of the P3D protein. Four of the five most immunoreactive domains are derived from small HAV proteins and/or encompass protein cleavage sites separating different HAV proteins.

BP000411-HAV-231: Recombinant HAV P3C

Source: E.coli-derived.
The 40 kDa protein contains the P3C immunodominant regions, amino acids 1643-1743.
Purity > 95%, by 10% PAGE.
Formulation: 10 mM CBB, pH9.6, 0.1% SDS and 50% glycerol.
Applications: WB, ELISA.

Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.

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