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Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal HARS Enzyme performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis.
BP000910-ENZ-268: Recombinant Human Histidyl-tRNA Synthetase
Source: E.coli-derived.
A single, non-glycosylated, polypeptide chain having a molecular mass of 55 kDa.
Purity > 95%, by RP-HPLC and SDS-PAGE.
Formulation: The protein solution contains 500 um NaCl and 10 mM Tris (pH 8.0) and 6 M Urea.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
Other HARS Enzymes:
Recombinant Human Histidyl-tRNA Synthetase, Sf9
Recombinant Human Histidyl-tRNA Synthetase, His Tag
HARS Antibodies:
HARS Polyclonal Antibody
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