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HARS Enzyme

Histidyl-tRNA synthetase, EC 6.1.1.21, Histidine-tRNA ligase, HisRS, HRS, FLJ20491, JO-1

Catalog No. Product Name Size List Price (US$) Quantity
BP000910-ENZ-268 Recombinant Human Histidyl-tRNA Synthetase 50 ug 160.00
BP000910-ENZ-268 Recombinant Human Histidyl-tRNA Synthetase 1 mg 1600.00
Description

Introduction
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis.

BP000910-ENZ-268: Recombinant Human Histidyl-tRNA Synthetase

Source: E.coli-derived.
A single, non-glycosylated, polypeptide chain having a molecular mass of 55 kDa.
Purity > 95%, by RP-HPLC and SDS-PAGE.
Formulation: The protein solution contains 500 um NaCl and 10 mM Tris (pH 8.0) and 6 M Urea.

Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.

Other HARS Enzymes:
Recombinant Human Histidyl-tRNA Synthetase, Sf9
Recombinant Human Histidyl-tRNA Synthetase, His Tag

HARS Antibodies:
HARS Polyclonal Antibody

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