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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal GRO α Protein performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
Chemokine (C-X-C motif) ligand 1 (CXCL1) is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimulating activity, alpha (MSGA-a). It is secreted by human melanoma cells, has mitogenic properties and is implicated in melanoma pathogenesis. CXCL1 is expressed by macrophages, neutrophilsand epithelial cells, and has neutrophil chemoattractant activity. CXCL1 plays a role in spinal cord development by inhibiting the migration of oligodendrocyte precursors and is involved in the processes of angiogenesis, inflammation, wound healing, and tumorigenesis. This chemokine elicits its effects by signaling through the chemokine receptor CXCR2. The gene for CXCL1 is located on human chromosome 4 amongst genes for other CXC chemokines.
BP000266-CHM-329: Recombinant Human GROα (CXCL1)
Source: E. coli-derived.
N-terminal sequence analysis: Ala-Ser-Val-Ala-Thr.
A single,non-glycosylated, polypeptide chain containing 73 amino acids and having a molecular mass of 7811 Dalton.
Determined by its ability to chemoattract human peripheral blood neutrophils using a concentration range of 10.0-100.0 ug/ml.
Purity > 97%, by SDS-PAGE and RP-HPLC.
Formulation: Lyophilized from a 0.2 um filtered concentrated (1 ug/ml) solution in 20 mM PB, pH 7.4, 50 mM NaCl.
Reconstitution: It is recommended to reconstitute the lyophilized CXCL1 in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.
Other GRO alpha Protein:
Recombinant Human GROα/MGSA (CXCL1), His Tag
GROalpha Antibody:
GROα Polyclonal Antibody
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