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GOPC Protein

GOPC, PDZ protein interacting specifically with TC10, CFTR-associated ligand, Fused in glioblastoma

Catalog No. Product Name Size List Price (US$) Quantity
BP002856-PRO-793 Recombinant human GOPC Protein 25 ug 160.00
BP002856-PRO-793 Recombinant human GOPC Protein 1 mg 2500.00
Description

Introduction
GOPC is a PDZ domain-containing Golgi protein which binds the extreme C terminus of proteins in a sequence-specific manner. GOPC participates in intracellular protein trafficking and degradation. GOPC regulates CFTR chloride currents and acid-induced ACCN3 currents by modulating cell surface expression of both channels. GOPC regulates the intracellular trafficking of the ADR1B receptor. GOPC takes part in autophagy. GOPC over expression results in CFTR intracellular retention and degradation in the lysosomes.

BP002856-PRO-793: Recombinant human GOPC Protein

Source: E. coli-derived.
Recombinant human GOPC Protein is a single, non-glycosylated polypeptide chain containing 198 amino acids (278-454 a.a.) and having a molecular mass of 21.5 kDa. The GOPC is fused to a 20 amino acid His Tag and purified by conventional chromatography.
Formulation: The GOPC protein solution contains 20 mM Tris-HCl pH-8, 1 mM DTT and 10% glycerol.

Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.

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