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Conditions of optimal GMPR1 Enzyme performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
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Introduction
GMP reductase 1 , also known as Guanosine 5'-monophosphate oxidoreductase 1, GMPR and GMPR1, is a member of the IMPDH/GMPR family. GMPR exsits as a homotetramer and catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. GMP reductase gene expression may be regulated by MITF. At least two different alleles are known.
BP001414-ENZ-570: Recombinant Human GMPR1 (Guanosine 5'-monophosphate oxidoreductase 1)
Source: E. coli-derived.
A single, non-glycosylated polypeptide chain containing 365 amino acids (1-345) and having a molecular mass of 39.5 kDa. GMPR is fused to a 20 amino acid His-tag at N-terminus.
Purity > 95%, by SDS-PAGE.
Formulation: The GMPR solution (1 ug/ml) contains 20 mM Tris-HCl buffer (pH8.0), 40% glycerol, 0.15 M NaCl and 1 mM DTT.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
Other GMPR1 Enzymes:
Recombinant Human GMPR1
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