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GM-CSF Protein

Granulocyte Macrophage Colony Stimulating Factor, MGI-1GM, Pluripoietin-alpha, Molgramostin, Sargramostim, CSF2, GMCSF

Catalog No. Product Name Size List Price (US$) Quantity
BP000176-CYT-221 Recombinant Human GM-CSF Protein 10 ug 160.00
BP000176-CYT-221 Recombinant Human GM-CSF Protein 1 mg 2925.00
Description

Introduction
Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) was first characterized as a growth factor that supports the in-vitro colony formation of granulocytes-macrophages progenitor cells (1, 2). It is a pleiotropic cytokine and a member of a family of endogenous cytokines of the hematopoietic system. GM-CSF is produced as a response to immune or inflammatory stimuli by activated cells of the hematopoietic system such as T cells, B cells, macrophages, mast cells and also fibroblasts and alveolar epithelial cells. It plays an important role in regulating the proliferation, differentiation, survival and activation of hematopoietic cells such as granulocytes and monocytes ,neutrophiles, basophiles and eosonophoiles, erythroid cells, megakaryocytes and T cells (3,4).

BP000176-CYT-221: Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) Protein

Source: E. coli-derived.
N-terminal sequence analysis: Ala-Pro-Ala-Arg-Ser.
Predicted molecular mass: 14477 Dalton.
The ED50 as determined by the dose-dependant stimulation of the proliferation of human TF-1 cells (human erythroleukemic indicator cell line) is < 0.1 ug/ml, corresponding to a Specific Activity of 11,100,000 IU/mg.
Purity > 98% by SDS-PAGE and RP-HPLC.
Formulation: GM-CSF was lyophilized after extensive dialysis against 2 mM sodium phosphate buffer pH= 7.4?.1.
Reconstitution: It is recommended to reconstitute the lyophilized Granulocyte Macrophage Colony Stimulating Factor in sterile 18 M?-cm H2O not less than 100?/ml, which can then be further diluted to other aqueous solutions.

Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month, 2 to 8°C under sterile conditions after reconstitution.
3 months, -20 to -70°C under sterile conditions after reconstitution.

Other GM-CSF Proteins:
Recombinant Porcine GM-CSF Protein
Recombinant Mouse GM-CSF Protein
Recombinant Monkey GM-CSF Protein
Recombinant Human GM-CSF Protein, Sf9
Recombinant Human GM-CSF Protein, Pichia
Recombinant Human GM-CSF Protein, His Tag
Recombinant Human GM-CSF Protein, HEK
Recombinant Human GM-CSF Protein
Recombinant Human GM-CSF Protein
Recombinant Human GM-CSF Protein
Recombinant Canine GM-CSF Protein
Recombinant Rat GM-CSF Protein

GM-CSF Antibodys:
GM-CSF Polyclonal Antibody
GM-CSF Monoclonal Antibody
GM-CSF Monoclonal Antibody

GM-CSF ELISA Kits:
Rat GM-CSF ELISA Kit
Mouse GM-CSF ELISA Kit

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