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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Conditions of optimal Gelsolin antibody performance should be determined experimentally by the investigator.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
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Or leave a message with a formal purchase
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Background
Gelsolin, a protein of leukocytes, platelets, and other cells, severs actin filaments in the presence of submicromolar calcium, thereby solating cytoplasmic actin gels. A gelsolin variant with 23 more N-terminal amino acids is a plasma component probably involved in the clearance of actin, the most abundant human protein, from the circulation. Gelsolin is located in 9q34. Plasma and cytoplasmic gelsolins are encoded by a single gene and contain a duplicated actin-binding domain.
PA000044-MA1044: Gelsolin Monoclonal Antibody
Mouse Monoclonal Antibody.
Specificity/Sensitivity: Human; rabbit. No cross reactivity with other proteins.
Applications: Western blot: At 0.5-1 ug/ml with the appropriate system to detect Gelsolin in cells and tissues. Immunohistochemistry(P): At 1-2 ug/ml to detect Gelsolin in formalin fixed and paraffin embedded tissues. Immunohistochemistry(F): At 1-2 ug/ml to detect Gelsolin in formalin or acetone fixed tissues.
Reactivity: Human, Rabbit.
Immunogen: Human plasma gelsolin.
Form of Antibody: Lyophilized from 1.2% sodium acetate, with 2 mg BSA and 0.01 mg NaN3 as preservative.
Clone: GEL-42.
Isotype: Mouse IgG1.
Storage/Stability: Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
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